Rokfos Infusion 100 ml

About Rokfos Infusion 100 ml

Rokfos Infusion 100 ml belongs to the class of medicines called ‘bisphosphonates’ used to treat osteoporosis (weak and brittle bones) caused by menopause or long-term steroid use. Rokfos Infusion 100 ml also treats Paget’s bone and high calcium levels caused by cancer. Osteoporosis is a bone disease that weakens and thins bones by decreasing bone density, common in post-menopausal women.  As the density of bones decreases, they weaken and are more likely to break.

Rokfos Infusion 100 ml contains Zoledronic acid that works by binding to the bone tightly and preventing the removal of calcium by osteoclasts (a type of bone cell that destroys bone tissue). This prevents osteoclasts from breaking down the bone and keeps the bones strong and minimizes the risk of bones breaking.

A doctor or nurse will administer Rokfos Infusion 100 ml. In some cases, you may experience headache, fever, nausea, dizziness, vomiting, back pain, diarrhea, pain in the muscles, joints, or bones, swelling, or pain at the infusion site. Most of these side effects of Rokfos Infusion 100 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Rokfos Infusion 100 ml or any other medicines, please tell your doctor. Avoid taking Rokfos Infusion 100 ml if you are pregnant or breastfeeding and consult a doctor. Rokfos Infusion 100 ml is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking Rokfos Infusion 100 ml if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Drive only if you are alert as Rokfos Infusion 100 ml may cause dizziness. Rokfos Infusion 100 ml may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw.

Uses of Rokfos Infusion 100 ml

Postmenopausal osteoporosis, Paget’s disease, Hypercalcemia (high level of calcium) in cancer

Medicinal Benefits

Rokfos Infusion 100 ml contains Zoledronic acid used to treat postmenopausal osteoporosis, Paget’s disease, and hypercalcemia of malignancy (bone cancer in which excess of calcium exits). Rokfos Infusion 100 ml binds to the bone tightly and prevents calcium removal by osteoclasts (a type of bone cell that destroy bone tissue). This prevents osteoclasts from breaking down the bone, strengthening bones, and minimizing the risk of bones breaking. Also, Rokfos Infusion 100 ml may reduce calcium levels in the blood by preventing calcium reabsorption from bones to the blood. Thus, it helps in treating high calcium levels in the blood caused by cancer.

Directions for Use

Rokfos Infusion 100 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rokfos Infusion 100 ml

• Headache
• Fever
• Nausea
• Dizziness
• Vomiting
• Back pain
• Diarrhoea
• Flu-like symptoms (chills, tiredness, muscle, and joint pain)
• Pain in the muscles, joints, or bones
• Swelling or pain at the infusion site

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Rokfos Infusion 100 ml or any other medicines, please tell your doctor. Avoid taking Rokfos Infusion 100 ml if you are pregnant or breastfeeding and consult a doctor. Rokfos Infusion 100 ml is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking Rokfos Infusion 100 ml if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Drive only if you are alert as Rokfos Infusion 100 ml may cause dizziness. If you are not able to take daily calcium supplements, have had sections of the intestine or some or all of the parathyroid glands in the neck surgically removed, have cancer, gum disease, poor dental health, or planned tooth extraction or kidney problem, inform your doctor before taking Rokfos Infusion 100 ml. If you are a smoker, inform your doctor before receiving Rokfos Infusion 100 ml as it may increase the risk of dental problems. Rokfos Infusion 100 ml may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw. You are recommended to drink at least 2 glasses of fluids before and after treatment with Rokfos Infusion 100 ml as advised by your doctor to prevent dehydration. Take calcium and vitamin D supplements as prescribed by your doctor as Rokfos Infusion 100 ml may reduce calcium levels in the blood.

Drug Interactions

Drug-Drug Interaction: Rokfos Infusion 100 ml may interact with antibiotics (gentamicin) and water pills (furosemide).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Avoid taking Rokfos Infusion 100 ml if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. If you have cancer, gum disease, poor dental health, or planned tooth extraction or kidney problem, inform your doctor before taking Rokfos Infusion 100 ml.

Drug-Drug Interactions Checker List:

• GENTAMICIN
• FUROSEMIDE

Safety Advice

ALCOHOL CAUTION – Interaction of alcohol with Rokfos Infusion 100 ml is unknown. Please consult a doctor before consuming alcohol with Rokfos Infusion 100 ml. PREGNANCY UNSAFE – Rokfos Infusion 100 ml is a category D pregnancy drug and is not recommended for pregnant women as it may harm an unborn baby. Please consult a doctor if you are pregnant. BREAST FEEDING UNSAFE – Rokfos Infusion 100 ml is contraindicated in breastfeeding mothers. Therefore, please consult a doctor if you are breastfeeding. DRIVING CAUTION – Rokfos Infusion 100 ml may cause dizziness. Therefore, avoid driving or operating machinery if you feel dizzy after taking Rokfos Infusion 100 ml. LIVER CAUTION – Take Rokfos Infusion 100 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. KIDNEY CAUTION – Take Rokfos Infusion 100 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Rokfos Infusion 100 ml if you have severe kidney problems. CHILDREN UNSAFE – Rokfos Infusion 100 ml is not recommended for children below 18 years as the safety and effectiveness were not established.

Habit Forming

No

Diet & Lifestyle Advise

• Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
• Eat daily a serving of broccoli, cabbage, bok choy (Chinese white cabbage), spinach, and other green leafy vegetables.
• Snack on calcium-rich nuts like Brazil nuts or almonds.
• Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
• Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
• Replace the meat with tofu or tempeh for extra calcium in your food.

Special Advise

• A preventive dental check-up is required before using Rokfos Infusion 100 ml as it has been reported to cause osteonecrosis of the jaw.
• A blood test is recommended before taking each dose of Rokfos Infusion 100 ml to monitor kidney functioning.
• Regular intake of calcium and vitamin D may be recommended by your doctor while taking treatment with Rokfos Infusion 100 ml.
• While using Rokfos Infusion 100 ml, you may experience musculoskeletal pain, in this case, stop taking Rokfos Infusion 100 ml and consult a doctor.