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Dargen 60mcg Pfs Injection 0.3ml

Dargen 60mcg Pfs Injection 0.3ml

4,900

Dargen 60mcg Pfs Injection 0.3ml belongs to the class of medication called ‘blood-forming agent’  primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells’ cancer).
  • Description
  • Additional Information

About Dargen 60mcg Pfs Injection 0.3ml

Dargen 60mcg Pfs Injection 0.3ml belongs to the class of medication called ‘blood-forming agent’  primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells’ cancer). Dargen 60mcg Pfs Injection 0.3ml helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn’t filter the blood, leading to anaemia.

Dargen 60mcg Pfs Injection 0.3ml contains a protein ‘Darbepoetin alfa’ which works by providing signals to the bone marrow to make more red blood cells. Dargen 60mcg Pfs Injection 0.3ml is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient ‘erythropoietin protein’ which aids in the formation of red blood cells, Dargen 60mcg Pfs Injection 0.3ml stimulates the production of this protein in the bone marrow.

Dargen 60mcg Pfs Injection 0.3ml will be injected by the healthcare provider. Do not self-administer. The most common side effects of Dargen 60mcg Pfs Injection 0.3ml are shortness of breath,  cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of Dargen 60mcg Pfs Injection 0.3ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to darbepoetin alfa or epoetin alfa, please inform your doctor before taking Dargen 60mcg Pfs Injection 0.3ml to avoid any complications. Also, mention all the other medications you are taking to affect the way Dargen 60mcg Pfs Injection 0.3ml works. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be signs that the body has stopped responding to Dargen 60mcg Pfs Injection 0.3ml.

Uses of Dargen 60mcg Pfs Injection 0.3ml

Anaemia (in cancer and chronic kidney disease)

Medicinal Benefits

Dargen 60mcg Pfs Injection 0.3ml is a human-made form of naturally occurring erythropoiesis-stimulating protein or erythropoietin (a hormone produced by the kidney’s specialized cells and is responsible for protecting red blood cells against destruction and also stimulates the cells of bone marrow to produce more amount of red blood cells). Deficiency of erythropoietin happens when a person is suffering from chronic kidney diseases, which in turn cause low red blood cells count causing anaemia.  This medicine is primarily indicated for treating anaemia (low red blood cell count) in persons with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer except for bone marrow or blood cells’ cancer. Dargen 60mcg Pfs Injection 0.3ml contains a protein ‘Darbepoetin alfa’ which works by providing signals to the bone marrow to make more red blood cells.

Directions for Use

Dargen 60mcg Pfs Injection 0.3ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dargen 60mcg Pfs Injection 0.3ml

  • Shortness of breath
  • Cough
  • Hypotension (low blood pressure)
  • Headache
  • Body aches
  • Diarrhoea
  • Injection site pain
  • Abdominal pain (stomach pain)

In-Depth Precautions and Warning

Drug Warnings

Dargen 60mcg Pfs Injection 0.3ml can enhance the risk of serious heart problems including heart attack so tell your doctor immediately if you notice shortness of breath, sudden numbness or weakness, chest pain, or trouble speaking or understanding. This medicine may also shorten survival time in some people with certain types of cancer. Inform your doctor before taking Dargen 60mcg Pfs Injection 0.3ml if you have heart disease, high blood pressure, kidney disease, stroke, heart attack, blood clot, seizure, or latex allergy. Do not take Dargen 60mcg Pfs Injection 0.3ml if you are pregnant or breastfeeding unless prescribed by the doctor. Dargen 60mcg Pfs Injection 0.3ml may affect a person’s ability to drive as it may cause convulsion during initial days of treatment, so a person taking Dargen 60mcg Pfs Injection 0.3ml should avoid driving or operating any machine. Dargen 60mcg Pfs Injection 0.3ml should not be given to children below 12 years of age, as safety and effectiveness have not been established. Avoid consuming alcohol along with Dargen 60mcg Pfs Injection 0.3ml as it could lead to increased dizziness and sleepiness.

Drug Interactions

Drug-Drug Interactions: Dargen 60mcg Pfs Injection 0.3ml may have interaction with other chemotherapy drugs (thalidomide),  immunosuppressant medication (cyclosporine),  antihypertensive medicines (captopril).

Drug-Food Interactions: Avoid alcohol consumption while taking Dargen 60mcg Pfs Injection 0.3ml as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Dargen 60mcg Pfs Injection 0.3ml may have interactions with disease conditions such as seizures, hemodialysis, hypertension, and thrombotic events

Drug-Drug Interactions Checker List:
  • THALIDOMIDE
  • CYCLOSPORINE
  • CAPTOPRIL

Safety Advice

  • Safety Warning
    ALCOHOL UNSAFE – Avoid consumption of alcohol while taking Dargen 60mcg Pfs Injection 0.3ml as it may increase dizziness and sleepiness.
  • Safety Warning
    PREGNANCY CAUTION – Avoid taking Dargen 60mcg Pfs Injection 0.3ml if you are pregnant unless prescribed by a doctor as Dargen 60mcg Pfs Injection 0.3ml is a pregnancy category C drug. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.
  • Safety Warning
    BREAST FEEDING CAUTION – Consult your doctor before taking Dargen 60mcg Pfs Injection 0.3ml; your doctor will decide whether Dargen 60mcg Pfs Injection 0.3ml can be taken by breastfeeding mothers or not.
  • Safety Warning
    DRIVING UNSAFE – Dargen 60mcg Pfs Injection 0.3ml causes convulsions (seizures), especially during the initial months of treatment. So, it is better not to drive or operate machinery unless you are alert.
  • Safety Warning
    LIVER CAUTION – Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
  • Safety Warning
    KIDNEY CAUTION – Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
  • Safety Warning
    CHILDREN CAUTION – Dargen 60mcg Pfs Injection 0.3ml should not be given to children as the safety and efficacy have not been established.

Habit Forming

No

Diet & Lifestyle Advise

  • Limit the consumption of fluids, salt, potassium, phosphorous, and other electrolytes.
  • Eat a low-protein diet, and get enough calories from the foods if you are losing weight.
  • Eat foods that are high in vitamin B12, iron, and folic acid can fulfil the deficiencies of happed in kidney disease.
  • Include a little number of healthy fats in your diet that give you enough energy to be active during the day; however, try to limit fats that make you fatty. Try to include olive oil, peanut oil, and corn oil into your diet.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Using essential oils for massages can help increase circulation.

Special Advise

  • Certain diagnostic tests like Complete blood count (CBC) can help check the count of red blood cells.
  • Have regular haemoglobin tests to check whether there is an improvement in the level of red blood cells after taking Dargen 60mcg Pfs Injection 0.3ml or not.

Additional information

Unit

1 VIAL

Product Type

Injection

Country Of Origin

India

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